|
ihope
6 Million ₫
|
iwish
18 Million ₫
|
ivip
30 Million ₫
|
|
|---|---|---|---|
Scope of works |
Popular |
||
|
Down syndrome
Trisomy 21
|
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|
Edwards syndrome
Trisomy 18
|
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Patau syndrome
Trisomy 13
|
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Turner syndrome
Monosomy X (45,XO)
|
|||
|
Klinefelter syndrome
Trisomy (47,XXY)
|
– | ||
|
Jacobs syndrome
Trisomy (47,XYY)
|
– | ||
|
XXX syndrome
Trisomy X (47,XXX)
|
– | ||
|
DiGeorge syndrome
22q11 deletion
|
– | ||
|
1p36 deletion syndrome
11p36.3 deletion
|
– | ||
|
Angelman syndrome
15q11-q13 deletion
|
– | ||
|
Prader-Willi syndrome
15q11-q13 deletion
|
– | ||
|
Cri-du-chat syndrome
5p15 deletion
|
– | ||
|
15 other microdeletion syndromes
Other deletions
|
– | – | |
|
20 skeletal mutations
Dysplasia genetic mutations
|
– | – | |
|
Features
|
|||
|
Detection rate
|
99.9% | 99.9% | 99.9% |
|
Turnaround (days)
|
5 | 7 | 10 |
|
Multiton supported
|
– | ||
|
Postnatal insurance (Million)
|
200 | 1,500 | 1,500 |
|
Amniocentesis fee supported (Million)
|
3.5 | 3.5 | 3.5 |
Notes
- Prices are quoted in VND and VAT exclusive.
- Turnaround counts on working days excluding sample collecting day and report releasing day as well as public holidays as stated by law.
- Postnatal insurance policies are applied for cases in which no abnormality has been detected in the ihope reports while the babies are born with syndromes within the detection ranges of the respective tests.
- If ihope results in positive, pregnancy could be decided based on the respective report. In case there is a desire to conduct an amniocentesis, the capital of 3.5 Million VND would be paid in full amount after the report is submitted.
20 microdeletion syndromes
Included in ihope23 package
| Syndrome | Chromosome location | Incidence rate | Clinical appearances |
|---|---|---|---|
| DiGeorge | 22q11 | 1/4,000 | Mental retardation, Learning disabilities, Congenital heart disease |
| 1p36 deletion | 1p36.3 | 1/5,000~1/10,000 | Mental retardation, Congenital heart disease, Epilepsy, Multi-organ abnormalities |
| Angelman | (mat)15q11-q13 (70%) | 1/12,000~1/20,000 | Mental retardation, Emotional problems, Language barrier, Hyperactivity disorder |
| Prader-Willi | (pat)15q11-q13 (70%) | 1/10,000~1/30,000 | Mental retardation, Emotional & Dietary problems |
| Wolf-Hirschhorn | 4p16.3 | 1/50,000 | Mental retardation, Congenital heart disease, Multi-organ abnormalities |
| Cri-du-chat | 5p15 | 1/20,000~1/50,000 | Mental retardation, Language barrier |
| Williams | 7q11.23 | 1/7,500~1/20,000 | Mental retardation, Congenital heart disease, Multi-organ abnormalities |
| Smith-Magenis | 17p11.2 | 1/15,000 | Mental retardation, Behavioral problems |
| Koolen-de Vries | 17q21.31 | 1/16,000 | Mental retardation, Epilepsy |
| 18q deletion | 18q | 1/40,000 | Mental retardation, Multi-organ abnormalities |
| Alagille | 20p11.23 | 1/70,000 | Congenital heart disease, Multi-organ abnormalities |
| Jacobsen | 11q | 1/100,000 | Mental retardation, Multi-organ abnormalities, Slow development |
| Hereditary neuropathy with liability to pressure palsy, HNPP | 17p11.2-12 | 2~5/100,000 | Dysfunction of nerve system |
| Rubinstein-Taybi | 16p13.3 | 1/100,000~1/125,000 | Mental retardation, Emotional problems |
| WAGR | 11p13 | 1/500,000~1/1,000,000 | Mental retardation, Multi-organ abnormalities |
| Potocki-Shaffer | 11p11.2 | Rare | Mental retardation |
| Miller-Dieker | 17p13.3 | Rare | Mental retardation, Epilepsy |
| 1q21.1 deletion | 1q21.1 | Rare | Congenital heart disease, Clotting problems, Skeletal disorders |
| Kleefstra | 9q34.3 | Rare | Congenital heart disease, Emotional problems, Ataxia |
| Phelan-Mcdermid | 22q13 | Rare | Congenital heart disease, Emotional problems, Epilepsy, Language barrier |
20 skeletal dysplasia mutations
Included in ihope23 package
| Gene | Mutation | Disorder | Incidence rate |
|---|---|---|---|
| FGFR2 | 833G>T 1024T>A 1052C>G |
Crouzon syndrome | 1/25,000~1/60,000 |
| FGFR2 | 870G>T 1019A>G |
Pfeiffer syndrome | 1/100,000 |
| FGFR2 | 755C>G 758C>G |
Apert syndrome | 1/65,000~1/88,000 |
| FGFR3 | 1138G>A or G>C | Achondroplasia | 1/15,000~1/40,000 |
| FGFR3 | 1620C>A or C>G | Hypochondroplasia | 1/15,000~1/40,000 |
| FGFR3 | 742C>T 746C>G 1108G>T 1111A>T 1118A>G 1949A>T 2419T>G or T>A 2421A>T |
Thanatophoric dysplasia type I | 1/20,000~1/50,000 |
| FGFR3 | 1948A>G | Thanatophoric dysplasia type II | 1/20,000~1/50,000 |
| FGFR3 | 749C>G | Muenke syndrome | 1/30,000 |
| FGFR3 | 1172C>A | Crouzon syndrome | 1/25,000~1/60,000 |
